|Product:||Colloidal gold contrast for small animal micro-CT imaging|
|Description:||Colloidal gold contrast agent for high resolution microCT angiography and tumor imaging. Offered exclusively by MediLumine and co-developed with Cytodiagnostics Inc., a leader in manufacture of gold nanoparticles for Biology and Medicine.|
|Application:||Micro-CT angiography and tumor imaging.|
|Particle size:||14 ±2 nm|
|Storage buffer:||10 mM Phosphate Buffered Saline (1x PBS)|
|Product information:||Certificate of Analysis|
Micro-CT Tumor Imaging
Image shows Mvivo™ Au nanoparticle uptake in brain tumor following IV injection (dose of 0.1 ml per 20 grams) into a NUDE mouse glioblastoma tumor transplant model established with injection of U251 stem cells. The blood pool contrast agent diffuses into extracellular space of tumor and enables longitudinal micro-CT imaging of tumor after a single injection. Image courtesy of CROmed.
3D reconstruction of mouse brain vasculature from µCT measurements acquired with Siemens Inveon multimodal imaging system. Courtesy of Dr. Michael Lamba, University of Cincinnati.
Axial slice showing vascular contrast for microCT scan 26 hours post-injection of Mvivo™ Au at doses of 0.1 ml (right), 0.15 ml (left), and 0.2 ml (top). Image courtesy of Dr. Timothy Doyle, Stanford University
micro-CT Imaging of Rodent Brain Vasculature
- C Tipton, M Lamba, Z Qi, K LaSance and C Tipton Micro-CT Based Quantification of Mouse Brain Vasculature: The Effects of Acquisition Technique and Contrast Material. Med. Phys. 43, 3459 (2016)