New CRO Services

CRO Services

MediLumine launches CRO services for method development, formulation characterization and non-GMP batch manufacture of potential therapeutic & imaging compounds used in the life sciences.

Our proprietary drug delivery, theranostic and imaging platforms employing lipid, polymer, polysaccharide, hydrogel, and nanoparticle technologies have made us a partner of choice for outsource of R&D in the life sciences.

USP, ASTM, ISO and custom tests available upon requests.

For quote requests and more information on our CRO services contact info@medilumine.com.

Formulation Development Services

  • Nanoparticle formulation development
  • Nanoemulsion formulation development
  • Nanoparticle conjugation with peptides and APIs
  • Organic/Inorganic synthesis
  • Microfluidizer & Ultrasonic processing
  • Autoclave sterilisation/Sterile Fill

Formulation Characterization Services

  • LC-MS
    • method development (one target compound)
    • LC-MS first sample and calibration
    • LC-MS second and consecutive sample in sequence
    • LC-MS-MS method development (one target compound)
    • LC-MS-MS first sample and calibration
    • LC-MS-MS second and consecutive sample in sequence
    • Molecular mass determination by LC-MS
    • LC-MS-MS Identification of unknown compounds in a sample
  • Protein/peptide analysis
    • Protein/peptide analysis by LC-MS
    • Protein/peptide molecular mass determination by LC-MS up to 200KD
    • Protein / peptide sequencing by LC-MS-MS
    • RNA analysis by HPLC
    • Protein / peptide analysis by HPLC
  • HPLC
    • HPLC method development (one target compound)
    • HPLC run, first sample and calibration
    • HPLC run, second and consecutive sample in sequence
    • HPLC triglyceride oil profile
  • UPLC
    • UPLC method development (one target compound)
    • UPLC run, first sample and calibration
    • UPLC run, second and consecutive sample in sequence
  • GC-MS residual solvents USP test
    • GC-MS method development (one target compound)
    • GC-MS analysis, liquid sample; first sample and calibration
    • GC-MS analysis, liquid sample; second and consecutive sampleGC-MS analysis, gas sample; first sample and calibration
    • GC-MS analysis, gas sample; second and consecutive sample
    • GC-MS analysis, head space analysis first sample and calibration
    • GC-MS analysis, head space analysis second and consecutive sample
    • GC-MS fatty acid methyl ester test

Testing Services

  • Identification of unknown compounds by GC-MS in a sample
  • bacterial endotoxin test
  • Osmolality test per USP 37 <785>
  • pH test with glass electrode USP 37 <791>
  • Viscosity test per USP 29 <911> by capillary viscometer method
  • Specific gravity test per USP 37 <841> method 1
  • NH3 or NH4+ analysis in gas or liquid
  • Heavy metals, USP
  • Refractive index of solid powder test :
    Range = 1.4 ‐ 1.64
    Range = 1.65 ‐ 1.70
    Range = 1.70 ‐ 1.80
    Range = 1.81 ‐ 2.00
  • Surface tension of water-based solutions
  • Freezing point to -35
  • Freezing point to -170
  • Solid content
  • Karl-Fisher water test
  • Boiling point test
  • Closed cup flash point test
  • Residue on ignition test
  • Acid Number
  • Peroxide Number
  • Iodine Number
  • Brookfield viscometry – kinematic, tixotropy
  • Polarimetry
  • Loss on drying
  • α, β, γ radiation and contamination with radionuclides
  • Microscopy imaging and sizing, phase contrast, dark field
  • Particle testing using dynamic light scattering
  • Zeta Potential
  • Number of Particles
  • Drug Release Test

LCMS. Ideal for formulation development, chemical identification, protein analysis, contaminants testing ....

LC-MS. Ideal for formulation development, chemical identification, protein analysis, contaminants testing ….

HPLC Testing

HPLC. Ideal for formulation development, HPLC method development (one target compound) HPLC run, chemical analysis, trygliceride profifle …

 

 

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