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Fenestra VC

Description

Fenestra VC contrast agent is an iodinated nanoemulsion used for longitudinal vascular studies that require the contrast agent to be completely cleared from the organism, for example in PET/CT studies that need to locate the ventrical of heart. Fenestra VC is retained in liver for three to four days after injection before being completely eliminated by the hepatobiliary system.

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Khare HA, Binderup T, Hag AMF, Kjaer A. Longitudinal imaging of murine atherosclerosis with 2-deoxy-2-[18F]fluoro-D-glucose and [18F]-sodium fluoride in genetically modified Apolipoprotein E knock-out and wild type mice. Sci Rep. 2023 Dec 27;13(1):22983. doi: 10.1038/s41598-023-49585-1. 

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Zhu G, Sun H, Wang J, Zhao Z, Bao J, Feng R, Zhou J, Jing Z. In Vivo Detection and Measurement of Aortic Aneurysm and Dissection in Mouse Models Using Microcomputed Tomography with Contrast Agent. Contrast Media Mol Imaging. 2019 Mar 6;2019:5940301. doi: 10.1155/2019/5940301.

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Jarr KU, Ye J, Kojima Y, Nanda V, Flores AM, Tsantilas P, Wang Y, Hosseini-Nassab N, Eberhard AV, Lotfi M, Käller M, Smith BR, Maegdefessel L, Leeper NJ. 18F-Fluorodeoxyglucose-Positron Emission Tomography Imaging Detects Response to Therapeutic Intervention and Plaque Vulnerability in a Murine Model of Advanced Atherosclerotic Disease-Brief Report. Arterioscler Thromb Vasc Biol. 2020 Dec;40(12):2821-2828. doi: 10.1161/ATVBAHA.120.315239. Epub 2020 Oct 22. 

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Flores AM, Hosseini-Nassab N, Jarr KU, Ye J, Zhu X, Wirka R, Koh AL, Tsantilas P, Wang Y, Nanda V, Kojima Y, Zeng Y, Lotfi M, Sinclair R, Weissman IL, Ingelsson E, Smith BR, Leeper NJ. Pro-efferocytic nanoparticles are specifically taken up by lesional macrophages and prevent atherosclerosis. Nat Nanotechnol. 2020 Feb;15(2):154-161. doi: 10.1038/s41565-019-0619-3. Epub 2020 Jan 27. 

 

$405.00

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